Iyad M Ayoub Selected Research

Sodium-Hydrogen Exchangers

5/2019	Sodium-Hydrogen Exchanger Isoform-1 Inhibition: A Promising Pharmacological Intervention for Resuscitation from Cardiac Arrest.
2/2011	AVE4454B--a novel sodium-hydrogen exchanger isoform-1 inhibitor--compared less effective than cariporide for resuscitation from cardiac arrest.
4/2009	Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction.
10/2007	Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism.
4/2005	Cariporide potentiates the effects of epinephrine and vasopressin by nonvascular mechanisms during closed-chest resuscitation.
4/2003	Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability.
4/2002	Myocardial protection during ventricular fibrillation by inhibition of the sodium-hydrogen exchanger isoform-1.

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Iyad M Ayoub Research Topics

Disease

17	Ventricular Fibrillation 05/2019 - 04/2002
8	Heart Arrest (Cardiac Arrest) 05/2019 - 06/2003
4	Stroke (Strokes) 01/2010 - 02/2007
4	Ischemia 07/2007 - 04/2002
3	Ischemic Contracture 04/2005 - 04/2002
2	Reperfusion Injury 01/2017 - 06/2003
2	Ventricular Tachycardia 01/2010 - 11/2005
1	Hyperventilation 02/2012
1	Left Ventricular Dysfunction 04/2009
1	Acidosis 04/2002

Drug/Important Bio-Agent (IBA)

7	Sodium-Hydrogen ExchangersIBA 05/2019 - 04/2002
6	cariporideIBA 02/2011 - 04/2002
3	Cytochromes c (Cytochrome c)IBA 04/2009 - 02/2007
2	Erythropoietin FDA Link 01/2013 - 07/2007
2	salicylhydroxamic acid (SHAM)IBA 04/2009 - 02/2007
2	Caspase 3 (Caspase-3)IBA 04/2009 - 11/2008
2	Caspase 9IBA 04/2009 - 11/2008
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2017
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2017
1	Mitochondrial Permeability Transition PoreIBA 01/2017
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 09/2014
1	Saline SolutionIBA 01/2013
1	zoniporideIBA 10/2007
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2007
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2007
1	Epinephrine (Adrenaline)FDA LinkGeneric 11/2005
1	HydrogenIBA 04/2003
1	SodiumIBA 04/2003

Therapy/Procedure

17	Resuscitation 05/2019 - 04/2002
2	Cardiopulmonary Resuscitation (CPR) 09/2014 - 02/2012
1	Extracorporeal Circulation 10/2007